منابع مشابه
an inverstigation into the shrinkage behavior (kinetics) of microfilled hybrid and nano dental composites
چکیده ندارد.
15 صفحه اولZic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets
The development of the nervous system is a time-ordered and multi-stepped process that requires neural specification, axonal navigation and arbor refinement at the target tissues. Previous studies have demonstrated that the transcription factor Zic2 is necessary and sufficient for the specification of retinal ganglion cells (RGCs) that project ipsilaterally at the optic chiasm midline. Here, we...
متن کاملTarget practice: Zic2 hits the bullseye!
A major challenge in biology is to unravel how the billions of neurons of the nervous system make appropriate functional connections. This is known to be a multistep developmental process that includes guiding, targeting and refinement of axons. In this issue of The EMBO Journal, Garcı́a-Frigola and Herrera show compelling evidence that, within the visual system, the same transcription factor (Z...
متن کاملChurchill, a Zinc Finger Transcriptional Activator, Regulates the Transition between Gastrulation and Neurulation
Gastrulation generates mesoderm and endoderm from embryonic epiblast; soon after, the neural plate is established within the epiblast-both events require FGF signaling. We describe a zinc finger transcriptional activator, Churchill (ChCh), which acts as a switch between different roles of FGF. FGF induces ChCh slowly; this activates Smad-interacting-protein-1 (Sip1), which blocks further induct...
متن کاملATP concentration regulates enzyme kinetics
Adenosine 5’-triphosphate (ATP) is the nearly ubiquitous “energy currency” of living organisms, and thus is a crucial participant in the majority of enzymatic reactions. The standard models in enzyme kinetics generally ignore the temporal dynamics of ATP because it is assumed to be present in large excess. However, this assumption may not hold in many situations of cellular stress where ATP con...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2000
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.97.4.1618